Home Video Posted August 2, 1993 and updated on January 22, 2010 Movie Info Full Review News Home Video Overall A When Augusto and Michaela Odone (Nick Nolte and Susan Sarandon) discover their son is dying from a rare disease, the couple begins a desperate search for a cure. Lorenzo's Oil is based on a true story. Violence A Sexual Content A Profanity A- Substance Use -- MPAA Rating: PG-13 Get Content Details The Guide to our Grades Lorenzo’s Oil The most recent home video release of this movie is April 6, 2004. Here are some details… Related home video titles: Other desperate parents look for ways to help their seriously ill children in the movies John Q, Extraordinary Measures, My Sisters Keeper and The Brooke Ellison Story. Related news about Lorenzo’s Oil Great Mother’s Day Movies - Part 1 Exemplary women and caregivers are portrayed in these movies you can share with Mom. 10 Famous Faces We Lost in 2014 Teddy's final good-bye is tender and touching and all the more poignant in light of Williams' death.